Effect of heptachlor on hepatic mitochondrial oxidative phosphorylation in rat.
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چکیده
منابع مشابه
Uncouplers of rat-liver mitochondrial oxidative phosphorylation.
1. The ability of a series of compounds to uncouple oxidative phosphorylation of rat-liver mitochondria has been investigated. 2. The compounds were: 2-amino-1,1,3-tricyanopropene; carbonyl cyanide phenylhydrazone and its m-chloro and p-trifluoromethoxy derivatives; 4,5,6,7-tetrachloro-, 5-chloro-4-nitro-, 5-nitro-and 4,5,6,7-tetrachloro-1-methyl-benzotriazole; 4-hydroxy-3,5-di-iodo-, 3,5-di-br...
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Objective: The use of non-enzymatic antioxidants in food supplements and proper exercise can have a positive effect on decreasing oxidative stress by free radical hunting. The purpose of this study was to investigate the effect of aerobic training and L-carnitine supplementation on some of the oxidative stress factors in the liver of diabetic rats. Materials and Methods: In this experimental s...
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Using high-resolution oxygraphy, we tested the changes of various parameters characterizing the mitochondrial energy provision system that were induced by peroxidative damage. In the presence of succinate as respiratory substrate, 3 mM t-butyl hydroperoxide increased respiration in the absence of ADP, which indicated partial uncoupling of oxidative phosphorylation. Low activity of coupled respi...
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Thyroxine is an ortho-para-hindered phenol and as such it has the structure necessary to form a relatively stable phenoxyl free radical. I f free radical stability is an important feature of its biological reactions, it is pertinent to determine whether there is any specificity rendered to the phenol by o-halogen or p-phenoxy substitution, In regard to the initial microsomal degradation reactio...
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Mitochondrial function is a key determinant of both excitability and viability of neurons. Here, we demonstrate seizure-dependent changes in mitochondrial oxidative phosphorylation in the epileptic rat hippocampus. The intense pathological neuronal activity in pilocarpine-treated rats exhibiting spontaneous seizures resulted in a selective decline of the activities of NADH-CoQ oxidoreductase (c...
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ژورنال
عنوان ژورنال: INDUSTRIAL HEALTH
سال: 1990
ISSN: 0019-8366,1880-8026
DOI: 10.2486/indhealth.28.151